Fig. 4

The molecular docking of luteolin with target proteins. The 3D images were derived from the online CB-Dock2 database (https://cadd.labshare.cn/cb-dock2). (A) Molecular docking of TP53 (PDB ID: 1AIE) with luteolin. (B) Molecular docking of TNF (PDB ID: 2R32) with luteolin. (C) Molecular docking of IL6 (PDB ID: 1ALU) with luteolin. (D) Molecular docking of AKT1 (PDB ID: 1UNQ) with luteolin. (E) Molecular docking of BCL2 (PDB ID:5VAU) with luteolin. (F) Molecular docking of STAT3 (PDB ID: 6NJS) with luteolin. (G) Molecular docking of JUN (PDB ID: 5T01) with luteolin. (H) Molecular docking of CASP3 (PDB ID: 1NMS) with luteolin.