Table 1 Antifungal susceptibility of Candida albicans from different sources to five common antifungal agents.
Antimicrobial agents | MIC (mg/L) | RVVC patients(n = 50) | Vaginal colonization(n = 50) | Z/χ²-value | P-value | |
|---|---|---|---|---|---|---|
Amphotericin B | Min | 0.125 | 0.06 | 3.426 | 0.017 | |
P25 | 0.5 | 0.25 | ||||
P50 | 0.5 | 0.5 | ||||
P75 | 0.5 | 0.5 | ||||
Max | 4 | 1 | ||||
Sensitivity rate (%) | 96 | 100 | - | 0.495 | ||
5-Fluorocytosine | Min | ≤ 0.015 | ≤ 0.015 | 3.876 | 0.007 | |
P25 | 0.06 | 0.03 | ||||
P50 | 0.25 | 0.125 | ||||
P75 | 0.5 | 0.25 | ||||
Max | 4 | 1 | ||||
Sensitivity rate (%) | 100 | 100 | - | 1.000 | ||
Fluconazole | Min | 0.06 | 0.03 | 5.241 | <0.001 | |
P25 | 0.25 | 0.125 | ||||
P50 | 1 | 0.5 | ||||
P75 | 4 | 1 | ||||
Max | ≥ 128 | 32 | ||||
Sensitivity rate (%) | 88 | 96 | - | 0.269 | ||
Voriconazole | Min | ≤ 0.015 | ≤ 0.015 | 2.563 | 0.049 | |
P25 | 0.06 | 0.03 | ||||
P50 | 0.125 | 0.06 | ||||
P75 | 0.25 | 0.125 | ||||
Max | 8 | 4 | ||||
Sensitivity rate (%) | 74 | 86 | 5.705 | 0.017 | ||
Itraconazole | Min | ≤ 0.015 | ≤ 0.015 | 2.674 | 0.036 | |
P25 | 0.03 | ≤ 0.015 | ||||
P50 | 0.125 | 0.06 | ||||
P75 | 0.25 | 0.125 | ||||
Max | 16 | 8 | ||||
Sensitivity rate (%) | 72 | 88 | 6.801 | 0.009 | ||
