Table 4 In vitro expression levels of three secreted hydrolases, ALS1, ALS3, HWP1 genes and biofilm formation by Candida albicans with different drug resistance.

Resistance to at least one of five antifungal drugs (n = 23)

0.39±0.18

0.53±0.22

0.49±0.26

0.63±0.22

2.84±0.78

3.62±1.04

2.64±0.87

Susceptible to all five antifungal drugs (n = 77)

0.20±0.09

0.57±0.23

0.53±0.25

0.69±0.17

2.49±1.14

3.20±1.33

2.28±0.87

t-value

8.579

-0.681

-0.747

-1.278

1.745

1.672

1.854

P- Value

<0.001

0.498

0.457

0.204

0.085

0.100

0.067

Effect size (OR, 95% CI)

2.13 (1.56–2.91)

0.89 (0.52–1.53)

0.86 (0.50–1.48)

0.78 (0.46–1.32)

1.24 (0.98–1.58)

1.31 (1.01–1.70)

1.27 (0.99–1.63)