Table 1 Characteristics of the stroke and control cohorts.
Stroke cohort1 (n = 62) | Control cohort1 (n = 43) | p value2 | |
|---|---|---|---|
Age (years) | 58 (52, 65) | 62 (54, 69) | 0.08 |
Sex, males | 82 (51) | 30 (13) | < 0.01 |
Risk factors & comorbidities | |||
Alcohol | 27 (17) | 24 (10) | 0.68 |
Tobacco | 37 (23) | 17 (7) | 0.02 |
Atrial fibrillation | 9.7 (6) | 0 (0) | 0.08 |
Hypertension | 61 (38) | 47 (20) | 0.13 |
Dyslipidemia | 40 (25) | 47 (20) | 0.53 |
Diabetes mellitus | 20 (12) | 19 (8) | 0.89 |
Obesity | 30 (18) | 35 (15) | 0.56 |
Clinical characteristics at stroke emergency | |||
mRS | 5.0 (4.0, 5.0) | - | |
NIHSS | 12.0 (7.8, 17.0) | - | |
NIHSS (motor) | 7.0 (4.0, 9.0) | - | |
Stroke laterality, left | 29 (47) | ||
Stroke type, ischemic | 73 (45) | ||
Ischemic etiology | |||
Cardioembolic | 22 (10) | - | |
Atherothrombotic | 22 (10) | - | |
Lacunar | 24 (11) | - | |
Others | 11 (5) | - | |
Undetermined | 20 (9) | - | |
Hemorrhagic etiology | |||
Hypertensive | 82 (14) | - | |
Lobar | 5.9 (1) | - | |
Undetermined | 12 (2) | - | |
Biomarker level at baseline visit | |||
Endostatin ng/mL | 132 (111, 164) | 109 (99, 140) | < 0.01 |
GDF-10 pg/mL | 1279 (844, 1942) | 977 (853, 1451) | 0.06 |
Human uPA pg/mL | 581 (475, 687) | 676 (562, 793) | 0.11 |
Human uPAR pg/mL | 2704 (2212, 3275) | 2558 (2234, 2894) | 0.11 |
