Table 2 Poststroke rehabilitation (RHB) characteristics at the baseline visit.

From: Identifying new blood biomarkers of neuroplasticity associated with rehabilitation outcomes after stroke

 

NO IRT1

(n = 17)

IRT1

(n = 45)

p value2

Inpatient rehabilitation

100 (17)

95.6 (43)

1

Day-hospital rehabilitation

0 (0)

4.4 (2)

1

Time stroke- RHB (days)

11 (8, 14)

14 (9, 19)

0.09

Time stroke-sample (days)

10 (6, 13.5)

14 (8.2, 19)

0.08

RHB hour/week, baseline

7.5 (5, 9)

15 (15, 16)

< 0.01

Functional scores

mRS

5 (3.2, 5)

4 (3, 5)

0.2

BI

23 (20, 36.5)

35 (20, 68)

0.12

CAHAI

18.5 (13, 82)

13 (13, 16)

0.02

FMA

9 (0, 59)

8.5 (4, 40.7)

0.94

FAC

0 (0, 2.7)

0 (0, 2)

0.78

MRC proximal upper limbs

2.5 (0, 3)

2 (0, 4)

0.99

MRC distal upper limbs

0.5 (0, 3.5)

1 (0, 4)

0.95

MRC proximal lower limbs

3 (2, 4)

2 (1, 4)

0.98

MRC distal lower limbs

1 (0, 3)

1 (0, 4)

0.34

Biomarker level

Endostatin ng/mL

139 (117, 180)

132 (111, 162)

0.61

GDF-10 pg/mL

1211 (815, 1752)

1385 (888, 1951)

0.63

Human uPA pg/mL

566 (459, 630)

618 (481, 734)

0.11

Human uPAR pg/mL

2668 (2112, 2944)

2819 (2449, 3434)

0.21

  1. Notes: 1% (n); median (IQR). 2Wilcoxon‒Mann‒Whitney U test; Pearson’s chi-square test; Fisher’s exact test. Abbreviations: RHB (Rehabilitation), mRS (modified Rankin Scale), BI (Barthel Index), CAHAI (Chedoke Arm and Hand Activity Inventory), FMA (Fugl-Meyer Assessment), FAC (Functional Ambulation Categories), MRC (Medical Research Council), GDF-10 (Growth and Differentiation Factor-10), uPA (urokinase Plasminogen Activator), uPAR (uPA Receptor).