Fig. 1 | Scientific Reports

Fig. 1

From: Dapagliflozin ameliorates high glucose-induced peritoneal fibrosis through downregulation of ENKUR/PI3K/AKT signaling pathway

Fig. 1

Expression of SGLT2, ENKUR and PI3K/AKT pathways in human peritoneal effluent HPMCs. (a) Morphological changes of HPMCs isolated and cultured from peritoneal dialysis effluents of PD patients of different ages (100x). (b) Immunofluorescence identification of isolated and cultured HPMCs from peritoneal dialysis effluents of PD patients. (c,d) Expression levels of SGLT2, ENKUR, COI-IV, a-SMA, E-cadherin and PI3K/AKT pathway in each group were detected by Western blot and qRT-PCR. HPMCs: human peritoneal mesothelial cells.**p < 0.01, ***p < 0.001 for ANOVA. Uncropped gels and blots were included in a Supplementary Information file.

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