Fig. 1 | Scientific Reports

Fig. 1

From: LINC02159 modulated the glycolysis and proliferation of TNBC cell via targeting miR-1285-3p/G6PI axis

Fig. 1

Highly expressed LINC01259 was correlated with the malignant progression of TNBC. (A) Expression of LINC02159 in adjacent normal tissues and TNBC tissues was detected by RT-qPCR. Higher levels of LINC02159 were found in TNBC tissues in comparison to that of the non-cancerous tissues. The experiment was performed with 50 biological replicates (n = 50). (B) LINC02159 was overexpressed in TNBC cell lines (MDA-MB-231, BT-549, HCC1937 and SUM159) compared with the normal cell MCF10A. The experiment was performed with 3 biological replicates. (C) TNBC patients in late cancer stage (III-IV, n = 21) carried higher abundance of LINC02159 than that of those in early cancer stage (n = 29). (D) Expression of LINC02159 in TNBC patients with bone metastasis (n = 19) was significantly higher compared with patients without metastasis (n = 31).

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