Table 3 Cytotoxic activity of methanol extracts of Kirkia tenuifolia engl against MCF-7 breast cancer cell line.
Con (µg/mL) | Absorbance at 570 nm | Average | SD | % Cell viability | IC50 value | |||
|---|---|---|---|---|---|---|---|---|
Control | – | 0.894 | 1.421 | 1.451 | 1.005364 | 0.271145 | 100 | |
MeOH extract | 50 | 1.005 | 0.882 | 0.859 | 0.915333 | 0.078501 | 91.045 | 111.66 µg/mL |
100 | 0.307 | 0.351 | 0.467 | 0.375 | 0.082656 | 37.29994 | ||
200 | 0.621 | 0.387 | 0.316 | 0.3515 | 0.20602 | 34.96247 | ||
Doxorubicin | 50 | 0.774 | 0.801 | 1.22 | 0.942818 | 0.423064 | 93.77882 | 423.09 µg/mL |
100 | 1.241 | 0.773 | 0.886 | 0.817 | 0.466499 | 81.26413 | ||
200 | 0.682 | 0.775 | 0.823 | 0.652909 | 0.442101 | 64.94258 | ||