Table 3 Clinical characteristics stratified by p.R181H carriership in the NCI TP53 database.
Characteristic | Carrier of p.R181H | |
|---|---|---|
Yes n = 10 (%) | No n = 1985 (%) | |
Sex | ||
Male | 3 (30) | 607 (33) |
Female | 7 (70) | 1224 (67) |
Mean age at first cancer onset (years) | 37 | 25 |
First cancer onset < 18 years | 1 (10) | 591 (30) |
Patients with multiple cancers | 0 | 531 (27) |
Patients with breast cancer | n = 6 (%) | n = 640 (%) |
|---|---|---|
Mean age at first breast cancer onset (years) | 37 | 34 |
First breast cancer onset < 40 years | 2 (50) | 400 (75) |
Cancer patients with only breast cancera | 6 (60) | 439 (26) |
Patients with multiple breast cancers | 0 | 150 (23) |
