Fig. 6 | Scientific Reports

Fig. 6

From: Homeostatic response of phospholipid pathways to PCYT2 deficiency and impaired de Novo synthesis of phosphatidylethanolamine

Fig. 6

Regulation of PS decarboxylation and phospholipid degradation by lipolysis. The mRNA and protein expression of PISD with and without Cho treatments showing that PISD mRNA decreased (A) but PISD protein was not changed (B,C) in KD cells relative to WT cells. There was a tendency to lower PISD protein after treatments with Cho however the differences were not significant (D,E). The enzyme activities of PLD (F) and cytosolic PLA2 (G) were significantly reduced in KD cells relative to the WT cells. The results from three independent experiments are expressed as means ± SEM and significant differences between treatments determined by t-test or one-way ANOVA. The results shown are from three separate experiments at (*P < 0.05) and (**P < 0.005).

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