Fig. 3

Validation of combination plate results against checkerboard assay for antifungal interaction testing. Left: FICi values of the ATCC 90,028 C. albicans reference strain with the Combination plate and Checkerboard assay, non-parametric t test shows no significant difference between the two methods. Right: Regression analysis of FICi values obtained from both methods for selected clinical isolates (those with the most synergistic and antagonistic FICi values), regression slope shown in read between 1.066 and 1.317 (95% CI, p = 0.001).