Fig. 5
From: Comprehensive lipid analysis of human meibum and tears
Type 2ω WdiE composition in human meibum and tears. Lipids were extracted from meibum and tears collected from healthy subjects (n = 7), and type 2ω WdiEs were analyzed via LC-MS/MS in MRM mode. (a and b) Total quantities of C16:1 FA- or C18:1 FA-containing type 2ω WdiEs in meibum (a) and tears (b), according to the degree of unsaturation of their diol–FA moieties. Values are presented as mean + SD. (c) Diol–FA moiety composition of C16:1 FA- or C18:1 FA-containing type 2ω WdiEs, in pie charts. Species present at < 1% were categorized as “Others”. The simplified structure of type 2ω WdiE, showing the analyzed moiety, is represented. (d and e) Total quantities of C50:2 diol–FA-containing type 2ω WdiEs in meibum (d) and tears (e), according to the degree of unsaturation of their FA moieties. Values are presented as mean + SD. (f) FA moiety composition of C50:2 diol–FA-containing type 2ω WdiEs, in pie charts. Species present at < 1% were categorized as “Others”. The simplified structure of type 2ω WdiE, showing the analyzed moiety, is represented. Sat, saturated; MonoU, mono-unsaturated; DiU, di-unsaturated.
