Table 6 SRF and HRF changes in subjects with different stages of DME after anti-VEGF treatment.

From: Shifting of the local inflammatory characteristics of diabetic macular edema manifested in SD-OCT after anti-VEGF treatment and associations with system inflammatory bioparameters

Parameters

Median (IQR)

Early DME (n = 37)

Advanced DME (n = 35)

Severe DME (n = 36)

Atrophic DME (n = 18)

P-value

Baseline SRF, n(%)

0.004

 Present

3(8.11)

14(40)

14(38.89)

3(16.67)

 

 Absent

34(91.89)

21(60)

22(61.11)

15(83.33)

SRF after treatment, n(%)

0.015

 Present

2(5.41)

5(14.29)

12(33.33)

3(16.67)

 

 Absent

35(94.59)

30(85.71)

24(66.67)

15(83.33)

 P-value

1.0

0.030

0.806

1.0

Baseline HRF, n (%)

0.018

 ≥ 30

6(16.22)

16(45.71)

17(47.22)

8(44.44)

 

 < 30

31(83.78)

19(54.29)

19(52.78)

10(55.56)

HRF after treatment, n (%)

0.033

 ≥ 30

5(13.51)

7(20)

15(41.67)

6(33.33)

 

 < 30

32(86.49)

28(80)

21(58.33)

12(66.67)

 P-value

1.0

0.041

0.813

0.733

  1. SRF subretinal fluid, HRF hyperreflective retinal foci.