Fig. 5 | Scientific Reports

Fig. 5

From: NCOA4-mediated ferroptosis conducive to EMT inhibition in colorectal cancer cells was achieved through the PI3K/AKT/mTOR pathway

Fig. 5

Gpx4 and xCT played roles in regulating EMT. (A) the effect of Gpx4 on EMT-related genes and xCT in HCT-116 cell; (B) quantitative analysis derived from (A), the results were from three experiments; (C) the effect of Gpx4 on EMT-related genes and xCT in SW480 cell; (D) quantitative analysis derived from (C), the results were from three experiments; (E) the effect of xCT on EMT-related genes and Gpx4 in HCT-116 cell; (F) quantitative analysis derived from (E), the results were from three experiments; (G) the effect of xCT on EMT-related genes and Gpx4 in SW480 cell; (H) quantitative analysis derived from (G), the results were from two experiments. @@,$$ p < 0.01 vs control; @@@, ###,$$$,%%%, ^^^ p < 0.01 vs control.

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