Table 1 Comparison of basic characteristics between the training set and validation set.

From: Development and validation of a machine learning model for critical progression risk in pediatric severe community-acquired pneumonia

 

Training set(n = 148)

Validation set(n = 63)

χ2/t/Z

P

Severe pneumonia

  

1.667

0.197

Non-cSCAP

105

39

  

cSCAP

43

24

  

Age (years)

0.37(0.16,1.14)

0.41(0.16,1.00)

-0.229

0.819

Gender

  

1.137

0.286

Male

92

44

  

Female

56

19

  

WBC(109/L)

9.74(7.26,13.17)

9.98(7.02,12.88)

-0.176

0.860

NEUT(109/L)

4.42(2.59,7.38)

4.71(3.10,8.64)

-0.851

0.395

LY(109/L)

3.74(1.82,5.63)

3.11(2.10,5.04)

-0.444

0.657

MONO(109/L)

0.85(0.54,1.26)

0.81(0.57,1.35)

-0.057

0.955

NEUT%(%)

48.80(32.40,70.38)

59.50(41.90,68.00)

-0.919

0.358

LY%(%)

41.00(18.80,54.50)

32.80(21.80,48.30)

-0.923

0.356

Hb(g/L)

111.49 ± 15.49

110.62 ± 14.85

0.380

0.705

RDW-CV(%)

14.20(13.40,14.80)

14.10(13.60,14.60)

-0.011

0.991

PLT(109/L)

368.09 ± 129.54

384.76 ± 141.93

-0.831

0.407

PCT((ng/ml)

0.34(0.13,0.56)

0.37(0.14,0.56)

-0.832

0.405

ALT(U/L)

29.00(19.25,41.75)

25.00(18.00,39.00)

-0.938

0.348

AST(U/L)

48.00(37.00,60.00)

46.00(38.00,60.00)

-0.196

0.845

TP(g/L)

65.85(61.43,70.55)

65.70(61.10,71.30)

-0.144

0.885

ALB((g/L)

41.05(37.53,43.70)

40.00(37.50,44.00)

-0.285

0.776

GLB(g/L)

25.41 ± 5.84

25.53 ± 6.07

-0.137

0.891

BUN(mmol/L)

3.35(2.44,4.37)

3.38(2.65,4.21)

-0.664

0.507

Cr(umol/L)

21.00(17.00,25.75)

18.00(15.00,23.00)

-2.050

0.052

LDH(U/L)

360.00(313.00,450.00)

380.00(321.00,412.00)

-0.010

0.992

CK-MB(U/L)

25.50(19.00,36.75)

25.00(15.00,33.00)

-1.161

0.246

CRP(mg/L)

5.00(2.23,14.59)

7.71(4.50,26.20)

-1.317

0.188

PT(s)

11.40(10.40,12.28)

11.30(10.40,12.20)

-0.700

0.484

Fib(g/L)

2.91(2.33,3.67)

3.41(2.49,4.28)

-1.354

0.176

DD(mg/L)

0.60(0.42,0.96)

0.68(0.43,1.15)

-0.776

0.438

NLR

1.19(0.61,3.73)

1.84(0.90,3.19)

-0.926

0.354

MLR

0.24(0.16,0.33)

0.25(0.17,0.39)

-0.982

0.326

PLR

106.66(67.49,181.77)

112.39(76.03,172.08)

-0.512

0.608

NMR

5.54(2.86,10.47)

5.95(3.00,11.82)

-0.713

0.476

SII

394.31(200.82,1300.36)

664.75(300.31,992.00)

-1.153

0.249

AGR

1.62(1.40,1.92)

1.57(1.39,1.80)

-0.432

0.665

  1. This table compares the basic characteristics of patients in the training and validation sets, showing no significant differences in age, gender, or baseline laboratory parameters (P > 0.05). Non-cSCAP refers to no critical severe community-acquired pneumonia, while cSCAP refers to critical severe community-acquired pneumonia. The variables compared include: white blood cell count (WBC), neutrophil count (NEUT), lymphocyte count (LY), monocyte count (MONO), neutrophil ratio (NEUT%), lymphocyte ratio (LY%), hemoglobin (Hb), red cell distribution width-coefficient of variation (RDW-CV), platelet count (PLT), procalcitonin (PCT), C-reactive protein (CRP), alanine aminotransferase (ALT), aspartate aminotransferase (AST), total protein (TP), albumin (ALB), globulin (GLB), creatinine (Cr), blood urea nitrogen (BUN), lactate dehydrogenase (LDH), creatine kinase isoenzyme MB (CK-MB), prothrombin time (PT), fibrinogen (FIB), D-dimer, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), neutrophil-to-monocyte ratio (NMR), systemic immune-inflammation index (SII), and albumin-globulin ratio (AGR).
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