Fig. 1

Information about 1174 cases with cardiac adverse events associated with 5-HT3RAs. A Distribution of occurrence years. B Types of cardiac adverse events. C Distribution of sex. D Distribution of age. E Distribution of adverse events outcomes. F TTO of 5-HT3RAs-related cardiac AEs. TTO time-to-onset, 5-HT3RAs 5-HT3 receptor antagonists, AEs adverse events. The pie chart on the left shows the proportional distribution of all TTO, while the right side one indicates the specific distribution of TTO within 30 days.