Fig. 2

Relationships between the intra-WMH T1w or T2w signal in the frontal and parietal lobes and the amyloid status. Boxplots comparing the intra-WMH T1w or T2w signal within the frontal and parietal lobes according to the amyloid status (positive/negative). Uncorrected p-values (p) of the linear model adjusted for age and univariate Cohen’s d (effect size) are indicated in the plot. Aβ(-): amyloid-negative (AV45 PET); Aβ(+): amyloid-positive (AV45 PET); CI: cognitively impaired; CU: cognitively unimpaired.