Table 6 Stratified associations of RPR with 90-day unfavorable outcomes follow AIS in different sensitivity analyses by sex, TG, CHD, previous stroke/TIA, age, pneumonia, FIB, ALB, hypertension, BMI, smoking, and AF.

Age(years)

0.463

<60

401

1.906 (1.270, 2.861) 0.002

60–70

552

1.353 (1.028, 1.780) 0.031

70–80

439

1.363 (1.085, 1.712) 0.008

≥ 80

290

1.579 (1.213, 2.056) < 0.001

Sex

0.897

Male

1052

1.465 (1.232, 1.742) < 0.001

Female

630

1.438 (1.151, 1.797) 0.001

TG

0.289

< 1.7mmol/L

1119

1.405 (1.206, 1.636) < 0.001

≥ 1.7mmol/L

563

1.691 (1.239, 2.308) < 0.001

Previous stroke/TIA

0.062

No

1542

1.489 (1.294, 1.714) < 0.001

Yes

140

0.680 (0.295, 1.571) 0.367

CHD

0.490

No

1308

0.946 (0.916, 0.977) < 0.001

Yes

374

0.963 (0.920, 1.008) 0.110

AF

0.070

No

1496

1.361 (1.164, 1.590) < 0.001

Yes

186

1.872 (1.361, 2.575) < 0.001

Pneumonia

0.194

No

1409

1.568 (1.336, 1.839) < 0.001

Yes

273

1.276 (0.979, 1.663) 0.071

BMI

0.364

<28 kg/m²

1541

1.509 (1.310, 1.739) < 0.001

≥ 28 kg/m²

141

1.867 (1.191, 2.927) 0.007

Hypertension

0.471

No

729

1.527 (1.261, 1.850) < 0.001

Yes

953

1.381 (1.134, 1.682) 0.0013

FIB

0.209

<4.0 g/L

1145

1.578 (1.328, 1.876) < 0.001

≥ 4.0 g/L

537

1.315 (1.047, 1.652) 0.019

ALB

0.083

< 35 g/L

381

1.243 (0.996, 1.552) 0.055

≥ 35 g/L

1301

1.596 (1.341, 1.901) < 0.001

Smoking

0.171

No

246

1.657 (1.403, 1.956) < 0.001

Yes

1436

1.378 (1.091, 1.741) 0.007