Table 1 Baseline information and outcomes of all patients with AECOPD.
All (n = 931) | NO PeHR (n = 634) | PeHR (n = 297) | p | |
|---|---|---|---|---|
Sex (Male) | 462 (49.6%) | 312 (49.2%) | 150 (50.5%) | 0.766 |
Race (White) | 616 (66.2%) | 419 (66.1%) | 197 (66.3%) | 1.000 |
Age (year) | 72.1 [64.7; 79.5] | 72.5 [65.1; 80.5] | 71.1 [64.0; 77.8] | 0.041 |
Length of hospital stay (day) | 10.00 [5.97; 16.9] | 9.03 [5.71; 15.1] | 12.2 [6.89; 21.6] | < 0.001 |
Length of ICU stay (day) | 3.08 [1.83; 6.16] | 2.48 [1.62; 4.60] | 5.43 [2.70; 9.93] | < 0.001 |
In-hospital mortality | 140 (15.0%) | 62 (9.78%) | 78 (26.3%) | < 0.001 |
7-Day mortality | 77 (8.27%) | 38 (5.99%) | 39 (13.1%) | < 0.001 |
14-Day mortality | 129 (13.9%) | 61 (9.62%) | 68 (22.9%) | < 0.001 |
28-day mortality | 175 (18.8%) | 92 (14.5%) | 83 (27.9%) | < 0.001 |
60-Day mortality | 190 (20.4%) | 100 (15.8%) | 90 (30.3%) | < 0.001 |
90-Day mortality | 269 (28.9%) | 148 (23.3%) | 121 (40.7%) | < 0.001 |
SOFA Score | 5.00 [3.00; 7.00] | 4.00 [2.00; 7.00] | 5.00 [3.00; 8.00] | 0.001 |
SAPS-II Score | 37.0 [29.0; 45.0] | 35.0 [29.0; 43.0] | 39.0 [32.0; 47.0] | < 0.001 |
Myocardial_Infarct | 233 (25.0%) | 158 (24.9%) | 75 (25.3%) | 0.978 |
Congestive_Heart_Failure | 550 (59.1%) | 375 (59.1%) | 175 (58.9%) | 1.000 |
Peripheral_Vascular_Disease | 127 (13.6%) | 81 (12.8%) | 46 (15.5%) | 0.307 |
Cerebrovascular_Disease | 86 (9.24%) | 59 (9.31%) | 27 (9.09%) | 1.000 |
Dementia | 72 (7.73%) | 57 (8.99%) | 15 (5.05%) | 0.049 |
Rheumatic_Disease | 49 (5.26%) | 36 (5.68%) | 13 (4.38%) | 0.502 |
Peptic_Ulcer_Disease | 17 (1.83%) | 14 (2.21%) | 3 (1.01%) | 0.312 |
Diabetes_Without_CC | 200 (21.5%) | 132 (20.8%) | 68 (22.9%) | 0.527 |
Diabetes_With_CC | 187 (20.1%) | 130 (20.5%) | 57 (19.2%) | 0.705 |
Paraplegia | 38 (4.08%) | 26 (4.10%) | 12 (4.04%) | 1.000 |
Renal_Disease | 278 (29.9%) | 198 (31.2%) | 80 (26.9%) | 0.209 |
Hemoglobin_ (g/dL) | 10.9 [9.25; 12.5] | 10.8 [9.12; 12.5] | 10.9 [9.30; 12.6] | 0.245 |
Platelets_ (K/uL) | 205 [152; 264] | 204 [148; 262] | 212 [161; 268] | 0.145 |
WBC_ (K/uL) | 10.5 [7.60; 14.2] | 10.0 [7.30; 14.0] | 11.1 [8.40; 14.7] | 0.002 |
Aniongap_ (mmol/L) | 14.0 [11.0; 17.0] | 14.0 [11.0; 17.0] | 14.0 [12.0; 17.0] | 0.337 |
Bicarbonate_ (mmol/L) | 25.2 [22.0; 30.0] | 26.0 [23.0; 31.0] | 25.0 [21.0; 29.0] | 0.017 |
Chloride_ (mEq/l) | 100 [95.0; 104] | 100 [96.0; 104] | 100 [94.0; 104] | 0.561 |
Creatinine_ (mg/dl) | 1.10 [0.80; 1.60] | 1.10 [0.80; 1.60] | 1.00 [0.70; 1.40] | 0.036 |
Glucose_ (mg/dL) | 138 [111; 181] | 140 [112; 180] | 137 [107; 182] | 0.696 |
Sodium_ (mmol/L) | 139 [136; 142] | 139 [136; 142] | 139 [135; 142] | 0.061 |
Potassium_ (mmol/L) | 4.40 [4.00; 4.90] | 4.40 [4.00; 4.97] | 4.40 [4.00; 4.80] | 0.281 |
Bun_ (mg/dL) | 24.0 [16.0; 39.0] | 24.0 [16.0; 39.8] | 23.0 [15.0; 37.0] | 0.120 |
INR_ | 1.20 [1.10; 1.48] | 1.20 [1.10; 1.43] | 1.20 [1.10; 1.50] | 0.556 |
PT_ (s) | 13.2 [11.8; 15.8] | 13.1 [11.8; 15.6] | 13.3 [11.8; 15.9] | 0.703 |
Heart_Rate (beats/min) | 85.6 [74.3; 97.3] | 80.6 [71.6; 89.8] | 102 [89.0; 110] | < 0.001 |
MBP_ (mmHg) | 79.0 [73.1; 86.1] | 79.0 [73.2; 86.1] | 78.8 [73.1; 86.8] | 0.801 |
Resp_Rate_ (beats/min) | 20.4 [18.3; 22.9] | 20.0 [18.0; 22.1] | 21.7 [19.2; 24.8] | < 0.001 |
Temperature (℃) | 36.8 [36.6; 37.0] | 36.8 [36.6; 37.0] | 36.8 [36.7; 37.1] | 0.022 |
Spo2_ (%) | 95.4 [93.7; 97.0] | 95.4 [93.6; 97.0] | 95.4 [93.9; 97.0] | 0.457 |
DM | 343 (36.8%) | 233 (36.8%) | 110 (37.0%) | 0.991 |
Hypertension | 429 (46.1%) | 292 (46.1%) | 137 (46.1%) | 1.000 |
Coronary Heart Disease | 324 (34.8%) | 225 (35.5%) | 99 (33.3%) | 0.569 |
Sepsis | 611 (65.6%) | 386 (60.9%) | 225 (75.8%) | < 0.001 |
Hemopurification | 77 (8.27%) | 41 (6.47%) | 36 (12.1%) | 0.005 |
Norepinephrine | 244 (26.2%) | 136 (21.5%) | 108 (36.4%) | < 0.001 |
Dopamine | 12 (1.29%) | 6 (0.95%) | 6 (2.02%) | 0.213 |
Dobutamine | 12 (1.29%) | 6 (0.95%) | 6 (2.02%) | 0.213 |
Phenylephrine | 65 (6.98%) | 35 (5.52%) | 30 (10.1%) | 0.016 |
Milrinone | 3 (0.32%) | 3 (0.47%) | 0 (0.00%) | 0.555 |
Beta_Bolk | 147 (15.8%) | 64 (10.1%) | 83 (27.9%) | < 0.001 |
Vasopressor Use | 289 (31.0%) | 164 (25.9%) | 125 (42.1%) | < 0.001 |
Invasive | 0.086 | |||
Other | 384 (41.2%) | 276 (43.5%) | 108 (36.4%) | |
Non-Invasive | 156 (16.8%) | 106 (16.7%) | 50 (16.8%) | |
Invasive | 391 (42.0%) | 252 (39.7%) | 139 (46.8%) | |
pH | 7.35 [7.28; 7.40] | 7.35 [7.29; 7.40] | 7.34 [7.26; 7.40] | 0.471 |
Po2 | 62.0 [45.0; 95.0] | 63.0 [45.9; 97.0] | 61.0 [44.0; 86.0] | 0.161 |
Pco2 | 54.0 [43.0; 67.0] | 54.0 [44.0; 67.0] | 55.0 [43.0; 67.0] | 0.799 |
