Fig. 5 | Scientific Reports

Fig. 5

From: Effects of female hormone withdrawal and ulipristal acetate on MED12 mutation positive and negative uterine leiomyomas using a xenograft model

Fig. 5

Summary of the GO terms, KEGG pathways, and IPA pathways altered by EP withdrawal, P withdrawal, and UPA administration. Gene ontology (GO) enrichment, KEGG pathway, and Ingenuity Pathway Analysis (IPA) pathway analyses were performed using DEGs in each treatment group in each subtype. The GO terms, KEGG pathways, and IPA pathways extracted in EP withdrawal (E(-)P(-)), P withdrawal (E(+)P(-)), and UPA administration (EP + UPA) were divided into functional categories which are considered to be important for the development of ULM, in MED12m(+)- and (-)-ULMs, respectively. The number of GO terms and pathways was manually tabulated and expressed by babble sizes with the numbers.

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