Fig. 5 | Scientific Reports

Fig. 5

From: Comprehensive analysis of ALYREF gene expression and its correlation with immunotherapy efficacy and circulating tumor cells in bladder cancer

Fig. 5

Single-Cell and Spatial Transcriptomic Landscape of ALYREF: (A–C) UMAP heatmaps generated from single-cell RNA-seq datasets (GSE149652, GSE130001, and GSE145281), visualizing the high-dimensional transcriptomic landscape of ALYREF in a two-dimensional space. (D–I) Bar charts computed from average gene expression across various cell types within the single-cell datasets, with visualization facilitated by ggplot2. These charts provide a clear representation of ALYREF expression patterns across different cell populations. (J) Spearman correlation analysis results displayed in a heatmap format, showing the correlation between proportions of specific cell types within each single-cell dataset, providing insights into the cellular composition associated with ALYREF expression. (K) Visualization of spatial transcriptomic expression of ALYREF across different tumors, offering a comprehensive view of its distribution and potential implications in the tumor microenvironment.

Back to article page