Table 3 Factors related to the CT findings (multivariate analysis).

(i) Osteolysis (present/absent)

Sort of ARA (BP vs. DMB)

0.346

0.128–0.932

0.036

(ii) Sequestrum separation (present / absent)

Age (years)

1.033

1.008–1.058

0.008

Site (upper jaw vs. lower jaw)

0.548

0.338–0.887

0.014

Primary disease (osteoporosis vs. ,malignant tumor)

0.279

0.170–0.456

< 0.001

Drug holiday (− vs. +)

1.712

1.120–2.618

0.013

Duration of ARA administration (months)

1.009

1.003–1.015

0.002

(iii) Periosteal reaction (present/absent)

Steroid use (− vs. +)

0.492

0.299–0.809

0.005

MRONJ stage (1 vs. 2 vs. 3)

2.547

1.884–3.442

< 0.001

Leukocytes (/µL/1000)

0.898

0.825–0.977

0.012

Lymphocytes (/µL/1000)

1.263

1.073–1.487

0.005

Serum albumin (mg/dL)

0.619

0.418–0.917

0.017

(iv) Mixed-type osteosclerosis (present/absent)

Site (upper jaw vs. lower jaw)

2.656

1.570–4.492

< 0.001

Primary disease (osteoporosis vs. ,malignant tumor)

1.541

1.025–2.315

0.037

Lymphocytes (/µL / 1000)

1.300

1.082–1.562

0.005

Serum albumin (mg/dL)

0.656

0.448–0.959

0.030

(v) Bone within bone (present/absent)

Drug holiday (- vs. +)

4.533

1.258–16.334

< 0.001

MRONJ stage (1 vs. 2 vs. 3)

6.212

2.439–15.817

< 0.001