Table 1 Metabolite concentrations between PRESS and sLASER sequences.

From: Comparative analysis of sLASER and PRESS techniques for magnetic resonance spectroscopy of the normal human brain

Metabolite

PRESS (mean ± SD)

sLASER (mean ± SD)

/tCr ΔMean %

/tCr P-value

/tCr FDR q-value

/tCr (mean ± SD)

CRLB (mean ± SD)

/tCr (mean ± SD)

CRLB (mean ± SD)

Cr + PCr

1.000 ± 0.010

4.4 ± 0.5

1.000 ± 0.000

5.1 ± 0.9

 + 0

NA

NA

NAA + NAAG

1.460 ± 0.179

2.2 ± 0.4

1.584 ± 0.241

3.0 ± 0.5

 + 8

0.0004

0.002*

Glu + Gln

1.705 ± 0.206

16.9 ± 2.8

1.729 ± 0.349

24.8 ± 7.2

 + 1

0.8091

0.914

Gly + mI

0.875 ± 0.170

25.0 ± 4.2

0.755 ± 0.133

29.8 ± 11.5

-14

0.0001

0.0013*

GPC + PCh

0.310 ± 0.023

23.7 ± 19.7

0.297 ± 0.038

13 ± 19.7

-4

0.3977

0.5303

  1. All metabolite concentrations were normalized to total creatine (i.e., Cr + PCr). PRESS, point-resolved spectroscopy; sLASER, semi-localization by adiabatic selective refocusing; tCr, total creatine; ΔMean %, percentage change of the mean; SD, standard deviation; FDR, false-discovery-rate; NA, not applicable; Cr, creatine; Gln, glutamine; Glu, glutamate; NAA, N-acetylaspartate; NAAG, N-acetylaspartylglutamate; PCr, phosphocreatine; mI, myo-Inositol; Gly, glycine; PCh, phosphocholine.
  2. *FDR q-value < 0.05 denotes statistical significance.
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