Fig. 2
From: Single-cell RNA sequencing identifies potential critical prognostic biomarkers in bladder carcinoma
CNVs in epithelial cells, DEGs and function enrichment analyses. A, CNVs in epithelial cells were inferred using the inferCNV method, revealing the presence of copy number alterations across the epithelial cell population. B, CNV scores were calculated for each epithelial cell. C, Epithelial cells were classified into low- and high-malignancy groups. D, DEG analysis of epithelial cells identified 473 upregulated genes and 106 downregulated genes. E-F, GO and KEGG enrichment analyses revealed significant enrichment in apoptosis-related signaling pathways and the IL-17 signaling pathway. The significance and functional annotations of the relevant pathways are shown in the figure.
