Table 1 Project overview and resources.

From: Molecular mechanisms of olanzapine against agitation in schizophrenia and bipolar disorder based on network pharmacology and molecular docking

Project

Databases and Tools

Source

Target collection

GeneCards

https://www.genecards.org/

SwissTargetPrediction

http://www.swisstargetprediction.ch/

CTD

https://ctdbase.org/

DisGeNET

https://www.disgenet.org/

Drug-disease target intersection

Venny 2.1.0

https://bioinfogp.cnb.csic.es/tools/venny

Bioinformatics platform

http://www.bioinformatics.com.cn/

Protein-protein interaction

STRING

https://string-db.org

Cytoscape 3.10.0

https://www.cytoscape.org/

Cytoscape CytoHubba plug-in

https://www.cytoscape.org/

GO and KEGG enrichment analysis

DAVID

https://david.ncifcrf.gov/

Bioinformatics platform

http://www.bioinformatics.com.cn/

Drug-pathway-target-disease network

Cytoscape 3.10.0

https://www.cytoscape.org/

Molecular docking

PubChem

https://pubchem.ncbi.nlm.nih.gov/

ChemBio3D Ultra 14.0

https://cambridgesoft-chembio3d-ultra.software.informer.com/14.0/

AutoDockTools 1.5.6

https://autodock.scripps.edu/

AutoDock Vina

https://vina.scripps.edu/

PDB

http://www.rcsb.org

DoGSiteScorer

https://proteins.plus/

PyMOL 2.4.1

https://pymol.org/

Discovery Studio 2021

https://www.3ds.com/products/biovia/discovery-studio

  1. CTD, Comparative Toxicogenomics Database; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; DAVID, Database for Annotation, Visualization, and Integrated Discovery; PDB, Protein Data Bank.