Table 3 Information on the eight core targets.
No. | Uniprot ID | Gene symbol | PDB ID | Protein name | Degree |
|---|---|---|---|---|---|
1 | P23560 | BDNF | 5UGG | Brain-derived neurotrophic factor | 114 |
2 | P01308 | INS | 4AJX | Insulin | 97 |
3 | P31749 | AKT1 | 3CQU | AKT serine/threonine kinase 1 | 86 |
4 | P04637 | TP53 | 5O1D | Tumor protein P53 | 68 |
5 | P05019 | IGF1 | 1IMX | Insulin-like growth factor 1 | 65 |
6 | P01138 | NGF | 5JFW | Nerve growth factor | 62 |
7 | P19838 | NFKB1 | 7LFC | Nuclear factor kappa B subunit 1 | 50 |
8 | P09038 | FGF2 | 1BFF | Fibroblast growth factor 2 | 45 |
