Fig. 3 | Scientific Reports

Fig. 3

From: Pathological changes and aquaporin-4 expression after bevacizumab treatment of traumatic penumbra in the rat brain

Fig. 3

TEM images of brain tissue from the TP region. The ultrastructural changes in the TP in TBI-NS groups, deep staining and pyknosis of the nucleus, the water content in the cytoplasm increased, the swelling of mitochondria, blood vessels and glial cells, the basement membrane of BBB was thickened. Bevacizumab reduced edema and stabilized the structure of the basement membrane (○:chromatin; Blue →: nuclear pyknosis, nuclear membrane rupture; blue *: chromatin aggregation at the edge; red ◀: mitochondrial swelling).

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