Table 5 Association between Fried Frailty Phenotypes and the probable mild cognitive impairment by sex. Abbreviations: K-MMSE, the Korean version of the Mini-Mental State Examination; OR, odds ratio; CI, confidence interval; pMCI, probable mild cognitive impairment; Ref, reference. Model 1 was unadjusted. Model 2 was adjusted for age, center, and intracranial volume. Model 3 was further adjusted for cohabitation, educational attainment, perceived social support scores, sleep duration, smoking status (men only), alcohol consumption, type 2 diabetes mellitus, hypertension, waist circumference, and total cholesterol. Smoking status was unadjusted in the women’s group due to influential points.
K-MMSE | Men (n=700) | Women (n=1357) | ||||||
|---|---|---|---|---|---|---|---|---|
OR (95% CI) | OR (95% CI) | |||||||
Robust (n=336) | Pre-frail (n=327) | Frail (n=37) | P-values | Robust (n=583) | Pre-frail (n=684) | Frail (n=90) | P-values | |
pMCI (<24) | ||||||||
Model 1 | Ref | 1.85 (0.90 to 3.83) | 5.23 (1.83 to 14.89) | 0.002 | Ref | 3.69 (2.34 to 5.81) | 10.08 (5.53 to 18.36) | <0.001 |
Model 2 | Ref | 1.39 (0.65 to 3.00) | 4.43 (1.37 to 14.3) | 0.013 | Ref | 2.86 (1.78 to 4.59) | 5.79 (3.02 to 11.09) | <0.001 |
Model 3 | Ref | 1.24 (0.56 to 2.75) | 3.75 (1.09 to 12.9) | 0.037 | Ref | 2.12 (1.29 to 3.49) | 3.94 (1.99 to 7.83) | <0.001 |
