Table 3 Summary of MEC90 and MEC99 results under different sample sizes in Monte Carlo simulation.

From: Determining the optimal ropivacaine concentration for spinal anaesthesia during day surgery for anorectal procedures: a dose-finding study

Indicator

N = 45

N = 100

N = 200

N = 400

MEC90 mean

0.21

0.211

0.208

0.204

MEC90 median

0.199

0.199

0.199

0.199

MEC90 SD

0.03

0.023

0.02

0.015

MEC90 95% CI width

0.122

0.071

0.067

0.058

MEC99 mean

0.269

0.285

0.29

0.292

MEC99 median

0.291

0.293

0.293

0.293

MEC99 SD

0.03

0.018

0.009

0.004

MEC99 95% CI width

0.098

0.059

0.018

0.017

  1. CI, confidence interval; SD, standard deviation.