Fig. 4 | Scientific Reports

Fig. 4

From: Influence of xanthine oxidase and inosine monophosphate dehydrogenase polymorphisms on 6-mercaptopurine treatment response in pediatric acute lymphoblastic leukemia

Fig. 4

Effect of the variants in the IMPDH1 gene on 6-MP treatment response in pediatric ALL. Effect of the rs2228075 (a, c) and rs2278294 (b, d) polymorphisms on the frequency of APC reduction. APC reduction refers to frequency of APC < 0.75 × 109 cells/L during the consolidation II and maintenance treatment phases in (a and b) and during maintenance phase only in (c and d). The number of individuals with median values for each genotype group is indicated along the p value for the difference between genotype groups.

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