Fig. 5 | Scientific Reports

Fig. 5

From: Influence of xanthine oxidase and inosine monophosphate dehydrogenase polymorphisms on 6-mercaptopurine treatment response in pediatric acute lymphoblastic leukemia

Fig. 5

Effect of the rs2228075 and rs2278294 combination on the frequency of APC reduction. APC reduction refers to frequency of APC < 0.75 × 109 cells/L during maintenance phase of the chemotherapy. All observed genotype combinations are included. Horizontal lines with corresponding p values next to the lines show pairwise comparisons between each genotype group and the wildtype. The number of individuals in each genotype group is displayed at the top of the boxplots.

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