Table 2 Hematological indices by stage versus controls (mean ± SD).
Parameter | Stage | Control (mean ± SD) | Stage (mean ± SD) | Δ [95% CI] | t(df) | p (scientific) | q (FDR) | Cohen’s d | Hedges’ g | n (ctrl/stage) |
|---|---|---|---|---|---|---|---|---|---|---|
Hb (mg/dl) | T-I | 12.70 ± 1.21 | 9.30 ± 0.22 | −3.40 [− 3.58 – −3.22] | −36.36 (205.1) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −2.96 | −2.95 | 215 / 25 |
T-II | 8.03 ± 0.35 | −4.67 [− 4.87 – −4.47] | −46.62 (202.3) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −4.15 | −4.14 | 215 / 38 | ||
T-III | 7.10 ± 0.29 | −5.60 [− 5.77 – −5.43] | −64.19 (259.9) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −5.56 | −5.55 | 215 / 105 | ||
T-IV | 5.62 ± 0.38 | −7.08 [− 7.26 – −6.90] | −78.94 (281.5) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −7.08 | −7.06 | 215 / 117 | ||
Hct | T-I | 41.90 ± 1.05 | 31.90 ± 1.22 | −10.00 [− 10.52 – −9.48] | −39.33 (28.3) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −9.36 | −9.33 | 215 / 25 |
T-II | 25.90 ± 1.95 | −16.00 [− 16.66 – −15.34] | −49.33 (40.9) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −13.06 | −13.02 | 215 / 38 | ||
T-III | 21.50 ± 0.92 | −20.40 [− 20.63 – −20.17] | −177.63 (232.6) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −20.21 | −20.16 | 215 / 105 | ||
T-IV | 17.90 ± 1.26 | −24.00 [− 24.27 – −23.73] | −175.52 (204.4) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −21.27 | −21.22 | 215 / 117 | ||
MCH (pg) | T-I | 30.70 ± 0.62 | 21.50 ± 1.44 | −9.20 [− 9.80 – −8.60] | −31.61 (25.0) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −12.35 | −12.31 | 215 / 25 |
T-II | 17.30 ± 1.06 | −13.40 [− 13.76 – −13.04] | −75.67 (41.6) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −19.08 | −19.02 | 215 / 38 | ||
T-III | 15.70 ± 1.21 | −15.00 [− 15.25 – −14.75] | −119.59 (131.3) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −17.47 | −17.43 | 215 / 105 | ||
T-IV | 11.90 ± 0.98 | −18.80 [− 19.00 – −18.60] | −188.03 (167.7) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −24.54 | −24.48 | 215 / 117 | ||
MCHC (g/dl) | T-I | 34.80 ± 0.59 | 25.60 ± 1.93 | −9.20 [− 10.00 – −8.40] | −23.71 (24.5) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −11.09 | −11.05 | 215 / 25 |
T-II | 22.70 ± 1.79 | −12.10 [− 12.69 – −11.51] | −41.28 (38.4) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −13.80 | −13.76 | 215 / 38 | ||
T-III | 19.20 ± 1.05 | −15.60 [− 15.82 – −15.38] | −141.71 (137.0) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −20.23 | −20.18 | 215 / 105 | ||
T-IV | 16.50 ± 1.51 | −18.30 [− 18.59 – −18.01] | −125.96 (135.6) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −18.06 | −18.01 | 215 / 117 | ||
MCV (fl.) | T-I | 93.60 ± 1.45 | 72.50 ± 2.98 | −21.10 [− 22.34 – −19.86] | −34.93 (25.3) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −12.64 | −12.60 | 215 / 25 |
T-II | 67.00 ± 1.79 | −26.60 [− 27.22 – −25.98] | −86.71 (46.0) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −17.67 | −17.62 | 215 / 38 | ||
T-III | 62.70 ± 2.07 | −30.90 [− 31.34 – −30.46] | −137.38 (155.5) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −18.41 | −18.37 | 215 / 105 | ||
T-IV | 58.50 ± 1.99 | −35.10 [− 35.51 – −34.69] | −168.05 (184.4) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −21.15 | −21.10 | 215 / 117 | ||
RBC (×10¹²/L) | T-I | 4.02 ± 0.30 | 2.79 ± 0.15 | −1.23 [− 1.30 – −1.16] | −33.87 (50.3) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −4.26 | −4.25 | 215 / 25 |
T-II | 2.25 ± 0.18 | −1.77 [− 1.84 – −1.70] | −49.64 (79.0) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −6.20 | −6.18 | 215 / 38 | ||
T-III | 1.83 ± 0.10 | −2.19 [− 2.23 – −2.15] | −96.61 (291.4) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −8.67 | −8.65 | 215 / 105 | ||
T-IV | 1.35 ± 0.17 | −2.67 [− 2.72 – −2.62] | −103.49 (329.4) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | −10.20 | −10.18 | 215 / 117 | ||
Serum ferritin (ng/ml) | T-I | 53.90 ± 5.15 | 112.00 ± 4.98 | + 58.10 [55.94–60.26] | 55.01 (30.3) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | 11.32 | 11.28 | 215 / 25 |
T-II | 129.00 ± 3.95 | + 75.10 [73.64–76.56] | 102.78 (61.6) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | 15.05 | 15.00 | 215 / 38 | ||
T-III | 147.00 ± 5.10 | + 93.10 [91.90–94.30] | 152.83 (208.3) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | 18.14 | 18.09 | 215 / 105 | ||
T-IV | 165.00 ± 7.41 | + 111.10 [109.58–112.62] | 144.31 (178.3) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | 18.39 | 18.35 | 215 / 117 | ||
TIBC (µg/100 ml) | T-I | 293.00 ± 9.52 | 472.00 ± 25.90 | + 179.00 [168.24–189.76] | 34.29 (24.8) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | 14.66 | 14.61 | 215 / 25 |
T-II | 528.00 ± 21.90 | + 235.00 [227.70–242.30] | 65.07 (39.5) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | 19.32 | 19.26 | 215 / 38 | ||
T-III | 593.00 ± 32.90 | + 300.00 [293.51–306.49] | 91.58 (112.6) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | 14.73 | 14.69 | 215 / 105 | ||
T-IV | 685.00 ± 26.90 | + 392.00 [386.92–397.08] | 152.51 (132.0) | < 1 × 10⁻¹⁶ | < 1 × 10⁻¹⁶ | 22.15 | 22.10 | 215 / 117 |
