Table 4 Group-Wise distribution of histopathological Findings.
From: Protective effect of dexpanthenol in tacrolimus-induced nephrotoxicity in rats
Groups | ||||
|---|---|---|---|---|
Control-SF (n = 6) | DEX (n = 8) | TAK (n = 8) | DEX + TAK (n = 8) | |
Expansion in Bowman’s Capsulen, (n) | ||||
No damage | 5 | 3 | 1 | – |
≤ 10% | – | 5 | 3 | 5 |
11–25% | 1 | – | 1 | 3 |
26–45% | – | – | 3 | – |
46–75% | – | – | – | – |
> 76% | – | – | – | – |
Tubular Necrosis, (n) | ||||
No damage | 6 | 8 | 4 | 7 |
≤ 10% | – | – | 1 | 1 |
11–25% | – | – | 3 | – |
26–45% | – | – | – | – |
46–75% | – | – | – | – |
> 76% | – | – | – | – |
Leukocyte Infiltration in Vasa Recta, (n) | ||||
No damage | 6 | 7 | 3 | 2 |
≤ 10% | – | 1 | – | 1 |
11–25% | – | – | 2 | 3 |
26–45% | – | – | 2 | 1 |
46–75% | – | – | 1 | 1 |
> 76% | – | – | – | – |
Tubular Regeneration, (n) | ||||
No damage | 4 | 1 | – | – |
≤ 10% | 1 | 2 | 1 | – |
11–25% | 1- | 4 | 3 | 4 |
26–45% | – | 1 | 3 | 2 |
46–75% | – | – | 1 | 2 |
> 76% | – | – | – | – |
Interstitial Inflammation, (n) | ||||
No damage | 1 | – | 1 | – |
≤ 10% | 4 | 5 | – | – |
11–25% | 1 | 3 | 4 | 4 |
26–45% | – | – | 2 | 2 |
46–75% | – | – | 1 | – |
> 76% | – | – | – | 2 |
Tubular Dilatation, (n) | ||||
No damage | 5 | 4 | 1 | – |
≤ 10% | 1 | 4 | 2 | 5 |
11–25% | – | – | 3 | 2 |
26–45% | – | – | 1 | 1 |
46–75% | – | – | 1 | – |
> 76% | – | – | – | – |
Mitosis, (n) | ||||
No damage | 6 | 5 | 1 | 2 |
≤ 10% | – | 3 | 7 | 6 |
11–25% | – | – | – | – |
26–45% | – | – | – | – |
46–75% | – | – | – | – |
> 76% | – | – | – | – |
Cast Formation, (n) | ||||
No damage | 5 | 5 | 1 | 6 |
≤ 10% | 1 | 3 | 3 | 2 |
11–25% | – | – | 1 | – |
26–45% | – | – | 2 | – |
46–75% | – | – | 1 | – |
> 76% | – | – | – | – |
Loss Off The Brush Border, (n) | ||||
No damage | 1 | 5 | 1 | – |
≤ 10% | 4 | 3 | 2 | 5 |
11–25% | 1 | – | 3 | 2 |
26–45% | – | – | 1 | 1 |
46–75% | – | – | 1 | – |
> 76% | – | – | – | – |
