Table 1 Characterization of biochemical parameters, body composition, and IR indices across study groups.
From: Associations between asprosin, insulin resistance, and oxidative stress in adults with obesity
Parameter | CG | O1 | O2 | O1 vs. CG* | O2 vs. CG** | O1 vs. O2*** |
|---|---|---|---|---|---|---|
Glucose 0 (mg/dL) | 98.24 (84.50–122.50) | 101.50 (83.50–133.00) | 107.90 (87.50–178.00) | 0.046 | < 0.0001 | < 0.0001 |
Glucose 60 (mg/dL) | 114.90 (69.50–226.00) | 122.60 (57.94–209.50) | 148.30 (79.00–282.50) | 0.083 | < 0.0001 | < 0.0001 |
Glucose 120 (mg/dL) | 95.87 (66.50–141.00) | 98.70 (56.50–169.00) | 114.80 (72,50–232.00) | 0.388 | < 0.0001 | < 0.0001 |
Glucose 180 (mg/dL) | 77.60 (40.00–112.00) | 87.49 (54.00–115.00) | 92.04 (70.00–144.50) | < 0.0001 | < 0.0001 | 0.009 |
Glucose 240 (mg/dL) | 88.24 (73.50–107.00) | 89.53 (70.50–117.50) | 90.68 (73.50–170.50) | 0.410 | 0.219 | 0.535 |
Insulin 0 (µU/mL) | 7.53 (2.20–14.27) | 10.95 (4.02–29.69) | 21.35 (7.13–95.62) | < 0.0001 | < 0.0001 | < 0.0001 |
Insulin 60 (µU/mL) | 61.29 (19.98–155.50) | 76.13 (22.79–165.90) | 135.20 (17.08–427.70) | 0.011 | < 0.0001 | < 0.0001 |
Insulin 120 (µU/mL) | 37.90 (7.47–145.30) | 38.42 (6.93–123.70) | 77.56 (6.63–332.90) | 0.811 | < 0.0001 | < 0.0001 |
Insulin 180 (µU/mL) | 9.90 (2.57–30.62) | 15.50 (1.57–52.40) | 37.19 (5.32–874.40) | 0.0005 | < 0.0001 | < 0.0001 |
Insulin 240 (µU/mL) | 7.23 (2.20–35.25) | 9.31 (1.27–53.50) | 17.46 (5.05–86.09) | 0.0004 | < 0.0001 | < 0.0001 |
C-peptide (ng/mL) | 1.86 (1.10–3.20) | 2.37 (1.38–6.19) | 3.56 (1.93–10.21) | < 0.0001 | < 0.0001 | < 0.0001 |
HbA1c (%) | 5.29 (4.50–6.10) | 5.30 (4.60–6.30) | 5.57 (4.60–6.60) | 0.864 | < 0.0001 | < 0.0001 |
CHOL (mg/dL) | 197.70 (135.00–410.00) | 189.80 (94.00–272.50) | 190.90 (103.50–377.50) | 0.6572 | 0.5991 | 0.7544 |
LDL (mg/dL) | 118.50 (49.35–328.10) | 115.20 (43.84–205.20) | 122.10 (49.69–299.50) | 0.8749 | 0.4797 | 0.2176 |
HDL (mg/dL) | 73.50 (42.26–118.10) | 61.45 (31.05–92.83) | 50.79 (29.27–92.86) | < 0.0001 | < 0.0001 | < 0.0001 |
TG (mg/dL) | 82.71 (41.00–203.50) | 103.20 (34.50–477.00) | 129.00 (48.00–428.50) | 0.0942 | < 0.0001 | < 0.0001 |
AST (U/I) | 19.54 (13.20–31.25) | 21.08 (8.80–50.40) | 23.84 (12.30–97.20) | 0.2663 | 0.0255 | 0.2063 |
ALT (U/I) | 17.63 (6.20–64.40) | 20.82 (6.25–86.35) | 30.05 (9.25–155.00) | 0.0534 | < 0.0001 | < 0.0001 |
CRP (mg/L) | 1.07 (0.15–5.51) | 1.86 (0.29–9.96) | 4.64 (0.12–33.72) | 0.0002 | < 0.0001 | < 0.0001 |
BMI (kg/m2) | 22.31 (16.70–24.90) | 27.67 (25.00–29.90) | 36.70 (30.10–60.60) | < 0.0001 | < 0.0001 | < 0.0001 |
Body weight (kg) | 62.11 (48.30–77.40) | 78.79 (61.50–107.8) | 107.9 (76.20–187.8) | < 0.0001 | < 0.0001 | < 0.0001 |
Fat mass (kg) | 16.87 (8.00–25.60) | 27.00 (14.50–41.80) | 45.98 (25.60–98.60) | < 0.0001 | < 0.0001 | < 0.0001 |
Muscle mass (kg) | 24.75 (19.70–37.40) | 28.81 (19.70–46.60) | 34.63 (22.30–52.60) | < 0.0001 | < 0.0001 | < 0.0001 |
TBW (kg) | 33.16 (27.00–48.30) | 38.04 (27.30–60.10) | 45.39 (31.40–67.60) | < 0.0001 | < 0.0001 | < 0.0001 |
WHR | 0.87 (0.79–0.96) | 0.95 (0.83–1.09) | 1.03 (0.84–1.30) | < 0.0001 | < 0.0001 | < 0.0001 |
RMR (kcal/day) | 1.26 (1.13–1.69) | 1.39 (1.11–1.95) | 1.61 (1.27–2.22) | < 0.0001 | < 0.0001 | < 0.0001 |
VAT mass (g) | 311.2 (48.00–619.00) | 892.40 (164.00–2608.00.00.00) | 2255.00 (494.00–5565.00.00.00) | < 0.0001 | < 0.0001 | < 0.0001 |
VAT volume (cm3) | 329.80 (51.00–656.00) | 945.90 (174.00–2764.00.00.00) | 2389.00 (524.00–5899.00) | < 0.0001 | < 0.0001 | < 0.0001 |
Adipose tusse (%) | 31.93 (17.20–42.40) | 38.44 (23.80–51.90) | 44.49 (28.80–57.70) | < 0.0001 | < 0.0001 | < 0.0001 |
Android fat mass (g) | 1214.00 (450,00–2095.00.00) | 2396.00 (1117.0–3975.0.0.0) | 4774.00 (2145.00–11704.00.00.00) | < 0.0001 | < 0.0001 | < 0.0001 |
Gynoid fat mass (g) | 3544.00 (1911.00–5156.00) | 4828.00 (2637.0–7767.0) | 7039.00 (3666.0–13909.0) | < 0.0001 | < 0.0001 | < 0.0001 |
HOMA-IR | 1.83 (0.39–3.5) | 2.58 (0.9–6.76) | 5.7 (0.0–34.62.0.62) | < 0.0001 | < 0.0001 | < 0.0001 |
TyG | 8.23 (7.52–9.24) | 8.43 (7.41–10.13) | 8.76 (7.70–10.20) | 0.0579 | < 0.0001 | < 0.0001 |
TyG-WHR | 3.11 (2.76–3.57) | 3.49 (2.86–4.31) | 3.88 (2.99–5.14) | < 0.0001 | < 0.0001 | < 0.0001 |
Quicki-I | 0.36 (0.32–0.47) | 0.34 (0.29–0.39) | 0.31 (0.24–0.36) | < 0.0001 | < 0.0001 | < 0.0001 |
Matsuda-I | 8.64 (3.5–19.8) | 6.31 (2.52–12.15) | 3.37 (0.59–10.54) | < 0.0001 | < 0.0001 | < 0.0001 |
