Table 3 Association between CRP and CKM syndrome, and the modification effects of CRP in the association of 3-year average concentration of air pollution with CKM syndrome.

From: Association of air pollutions and systemic inflammation with early cardiovascular-kidney-metabolic syndrome among middle-aged and elderly adults: a cross-sectional study from CHARLS

Models

CRP-CKM

Air pollution-CKM

Pinter

OR and 95%CI

P

OR and 95%CI

P

Model 4

 CRP

1.207 (1.126, 1.295)

 < 0.001***

—

–

–

Model 5

 PM2.5 + CRP

1.210 (1.128, 1.298)

 < 0.001***

1.220 (1.094, 1.361)

 < 0.001***

 

 PM10 + CRP

1.207 (1.125, 1.296)

 < 0.001***

1.264 (1.133, 1.409)

 < 0.001***

 

SO2 + CRP

1.207 (1.125, 1.297)

 < 0.001***

1.227 (1.097, 1.373)

 < 0.001***

 

 NO2 + CRP

1.210 (1.128, 1.298)

 < 0.001***

1.194 (1.070, 1.332)

0.001**

 

O3 + CRP

1.207 (1.126, 1.295)

 < 0.001***

1.138 (1.021, 1.268)

0.019*

 

 CO + CRP

1.208 (1.126, 1.295)

 < 0.001***

1.164 (1.044, 1.298)

0.006**

 

Model 6

 PM2.5 + CRP + PM2.5 × CRP

1.216 (1.130, 1.307)

 < 0.001***

1.251 (1.087, 1.439)

0.002**

0.089*

 PM10 + CRP + PM10 × CRP

1.239 (1.147, 1.339)

 < 0.001***

1.389 (1.203, 1.603)

 < 0.001***

0.039**

 SO2 + CRP + SO2 × CRP

1.234 (1.143, 1.332)

 < 0.001***

1.356 (1.156, 1.590)

 < 0.001***

0.035**

 NO2 + CRP + NO2 × CRP

1.211 (1.128, 1.301)

 < 0.001***

1.202 (1.045, 1.382)

0.010*

0.158

 O3 + CRP + O3 × CRP

1.220 (1.134, 1.313)

 < 0.001***

1.205 (1.040, 1.396)

0.013*

0.062*

 CO + CRP + CO × CRP

1.211 (1.128, 1.301)

 < 0.001***

1.191 (1.034, 1.370)

0.015*

0.095*

  1. Model 4, a univariate model that included only CRP; Model 5, both CRP and each air pollutant were incorporated as independent variables; Model 6, an interaction model that included CRP, an air pollutant, and their interaction (CRP × air pollutant). *P < 0.05; **P < 0.01; ***P < 0.001 for the association of CRP/air pollution and CKM. *P < 0.10; **P < 0.05 for interactions of CRP and air pollution.
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