Table 4 Performance investigation of the biosensor for different cancerous analytes.

From: Advanced SPR biosensor with optimized gold-TiO2 D-shaped photonic crystal fiber for precise multi-cancer detection

Cancer type

Cell type

RI range

Resonance wavelength (nm)

Wavelength sensitivity (nm/RIU)

Amplitude sensitivity (RIU− 1)

Sensor resolution (RIU)

FOM (RIU− 1)

Skin

Basal

1.36–1.38

0.7–0.78

4000

– 569

2.5 × 10− 5

74.83

Cervical

HeLa

1.368–1.392

0.73–0.94

8750

– 1621.8

1.14 × 10− 5

163.7

Blood

Jurkat

1.376–1.390

0.76–0.91

10714.28

– 1826.77

9.33 × 10− 6

222.61

Adrenal Gland

PC12

1.381–1.395

0.79–1

15,000

– 1436.24

6.66 × 10− 6

360.12

Breast

MDA-MB-231

1.385–1.399

0.85–1.3

32142.85

– 736.963

3.11 × 10− 6

683.32