Fig. 2
From: Interrogating subclonal heterogeneity of liver cancer with single-cell multi-omics analysis
Gene expression heterogeneity between CMN and SN, and primary and satellite lesions. (A) Box plot showing the immune cell type proportion comparison between Confluent Multi-Nodular (CMN) and Single Nodular (SN). P values represent results of Wilcoxon test. (B) Box plot showing the cell–cell interaction counts comparison between CMN and SN samples in 10x-excluded cells(left) and drop-seq-only cells (right).P values represent results of Wilcoxon test. (C) Box plot showing differential pathways of cell–cell interaction between CMN and SN samples.P values represent results of Wilcoxon test. (D) Box plot showing the immune cell type proportion comparison between primary tumor (pt) and satellite tumor (st).P values represent results of Wilcoxon test. (E–F) Box plot showing the cell–cell RNA expression level correlation comparison between pt and st in CMN (E) and SN (F) samples. P values represent results of Wilcoxon test. (G) Dot plot showing the gene ontology (biology process) term result of common down-regulated genes in satellite tissue of HCC1.and HCC6.
