Table 1 Inhibitory activity of Zanthoxylym Caribaeum aqueous extract.

Species	Collection ID^a/Origin^b	Phenotype	Inhibitory diameter^c			MIC^d (× 10³ µg/mL)	MIC of kanamycin (µg/mL)
Species	Collection ID^a/Origin^b	Phenotype	n	mean	± sd (mm)	MIC^d (× 10³ µg/mL)	MIC of kanamycin (µg/mL)
Escherichia coli	ATCC25922^e	Gram-, wild type	8	6.7	± 0.2	250	2
Escherichia coli	EC335/Bovine feces^f	Gram-, ESBL	4	6.0	± 0.0	250	–
Klebsiella pneumoniae	ATCC700603	Gram-, ESBL	6	7.4	± *0.6*	125	–
Acinetobacter baumannii	Ab_161/Environment	Gram-, wild type	6	7.2	± *0.3*	250	–
Enterococcus faecalis	ATCC51299	Gram + , resistant	6	6.0	± 0.0	–	32
Staphylococcus aureus	ATCC25923	Gram + , wild type	6	7.5	± *0.6*	31	20
Staphylococcus aureus	SA024/Pig nasal swab	Gram + , MRSA	4	7.3	± *0.9*	16	20
Pseudomonas aeruginosa	ATCC27853	Gram-, wild type	2	8.0	± *2.0*	250	–
Pseudomonas aeruginosa	Elo_159R_020/Sediment	Gram-, resistant	4	6.6	± 0.3	–	–

^aReference strains have been supplied by the American Type Culture Collection (ATCC).
^bAnimal- and environmental-isolates were collected by the Institute Pasteur of Guadeloupe.
^cInhibitory diameters were expressed as mean in mm ± standard deviation (sd).
^dMIC values were expressed as values corresponding to the read of three independent experiments at the lowest concentrations that yielded no visible growth in the broth dilution assay. The missing MIC values corresponded to strains that had not been tested.
^eE. coli wild type used as positive test of Z. caribaeum inhibitory activity.
^fESBL resistant E. coli used as negative test for Z. caribaeum inhibitory activity.
Significant values are in [bold/bolditalic]. Inhibitory diameters are summarized as mean ± standard deviation (sd). MIC: Minimum Inhibitory Concentration, ESBL: extended-spectrum beta-lactamase, MRSA: methicillin-resistant Staphylococcus aureus.

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