Fig. 1 | Scientific Reports

Fig. 1

From: GADD45β inhibits hepatic lipogenesis through the AMPK/SREBP1 pathway via reducing the ubiquitination-mediated degradation of SIRT1

Fig. 1

Hepatic GADD45β expression was decreased in MASLD. (A, B) GADD45β mRNA expression levels in two different MASLD GEO datasets. (C) GADD45β mRNA expression levels in the livers of control diet-fed (CON) and methionine- and choline-deficient (MCD) diet-fed mice (n = 6). (D) GADD45β protein expression levels in the livers of control diet-fed mice (CON) and methionine- and choline-deficient diet-fed mice (MCD) (n = 6). nsP > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001.

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