Fig. 6

GADD45β directly interacted with SIRT1. (A) GADD45β and SIRT1 mRNA expression in HepG2 cells after the overexpression of GADD45β. (B) Coimmunoprecipitation (co-IP) of GADD45β with SIRT1 proteins in HepG2 cells. The co-IP and western blot data shown are representative of at least 3 independent experiments with consistent results.