Fig. 4 | Scientific Reports

Fig. 4

From: Polyethylene microplastics disrupt renal function, mitochondrial bioenergetics, redox homeostasis, and histoarchitecture in Wistar rats

Fig. 4

Renal oxidative stress and inflammatory markers following exposure to polyethylene microplastics (PE-MPs). Bar graphs represent mean ± SEM (n = 5/group) for a Ascorbic acid (AA), b reduced glutathione (GSH), c catalase (CAT), d glutathione-S-transferase (GST), e superoxide dismutase (SOD), f malondialdehyde (MDA), g nitric oxide (NO), and h myeloperoxidase (MPO) in renal tissue. PE-MPs exposure at both 15 and 60 mg/kg bw significantly reduced antioxidant defences (AA, GSH, CAT, SOD), elevated oxidative stress markers (MDA, NO) and inflammatory enzyme MPO (*p < 0.05 to ***p < 0.001), indicating dose-dependent redox imbalance and renal inflammation. Statistical analysis was performed using one-way ANOVA followed by Tukey’s post hoc test.

Back to article page