Table 2 Characteristics of the follow-up population diagnosed with gastric cancer and studied for PD-L1 overexpression.

From: PD-L1 expression in gastric cancer assessed with antibodies 28-8 and 22C3

Follow-up patients

Characteristic

 

Male

Female

Total

p-value

n

 

20 (58.8%)

14 (41.2%)

34 (100%)

 

Age (SD)

 

62.1 (10.9)

55 (14.4)

59 (12.7)

 

Differentiation

Poorly

7 (35%)

5 (35.7%)

12 (35.3%)

0.9

Moderate

4 (20%)

3 (21.4%)

7 (20.6%)

Non-specific

9 (45%)

6 (42.9%)

15(44.1%)

Lauren classification

Tubular-intestinal patron

1 (5%)

0 (0%)

1 (3%)

 

Rings cells

2 (10%)

4 (28.6%)

6 (17.6%)

 

PD-L1 clone 22c3

 

20 (100%)

14 (100%)

34 (100%)

 

Positive

6 (30%)

6 (42.9%)

12 (35.3)

 

Negative

14 (70%)

8 (57.1%)

22 (64.7%)

 

CPS 1–4

0 (0%)

4 (66.7%)

4 (33.3%)

 

CPS 5–9

3 (50%)

0 (0%)

3 (25%)

 

CPS > 10

3 (50%)

2 (33.3%)

5 (41.7%)

 

Metastasis

Yes

1 (5%)

5(35.7%)

6(17.6%)

(OR: 0.09 (0.009–0.9.009.9 IC 95% p = 0.02)

No

19 (95%)

9 (64.3%)

28 (82.4%)

Area

Cardioesophageal Junction

0 (0%)

1 (20%)

1 (16.6%)

 

Peritoneum

0 (0%)

2 (40%)

2 (33.3%)

 

Cervical Lymph Node

1 (100%)

0 (0%)

1 (16.6%)

 

Round Ligament

0 (0%)

1 (20%)

1 (16.6%)

 

Gastrocolic Ligament

0 (0%)

1 (20%)

1 (16.6%)

 

Immunotherapy

Yes

8 (40%)

4 (28.6%)

12 (35.3%)

 

No

12 (60%)

10 (71.4%)

22 (64.7%)

 

PD-L1 positive

2 (33.3%)

2 (33.3%)

4 (33.3%)

 

PD-L1 negative

6 (42.9%)

2 (25%)

8 (66.7%)