Fig. 10

RMSD profiles of NOX (2CDU) and its complex with lignan during molecular dynamics simulations. RMSD of the unbound NOX protein at 1 ns (A) and 10 ns (B). RMSD of the 2CDU–lignan complex at 1 ns (C) and 10 ns (D). The complex exhibited minimal structural deviation (~ 0.2 nm) throughout the simulation, indicating stable binding and overall conformational equilibrium.