Table 1 Comparison of baseline demographic and laboratory data with 3-Month Follow-Up data for each studied group in H pylori positive patients.
Vonoprazan (50 patients) | Lansoprazole (50 patients) | p value | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Age (Independent t test) | ||||||||||
Mean ± SD | 53.46 ± 11.55 | 53.02 ± 10.27 | 0.841 | |||||||
Range | 30–79 | 34–77 | ||||||||
Sex, N (%) (Chi square) | ||||||||||
Male | 27(54) | 27(54) | 1 | |||||||
Female | 23(46) | 23(46) | ||||||||
Baseline | 3months follow up | Baseline | 3months follow up | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
Median(IQR) | Range | Median(IQR) | Range | p value | Median(IQR) | Range | Median(IQR) | Range | p value | |
BMI | 27(26–29) | 22–36 | 27(25–30) | 22–36 | 0.275 | 27(26–28) | 24–33 | 27(26–28) | 24–34 | 0.276 |
SBP | 130(120–135) | 110–155 | 130(120–135) | 100–150 | 0.478 | 130(125–135) | 120–170 | 130(125–135) | 120–150 | 0.394 |
DBP | 80(70–85) | 60–100 | 80(70–90) | 60–100 | 0.541 | 75(70–80) | 70–110 | 80(75–90) | 60–100 | 0.312 |
creatinine | 1.7(1.5–1.8) | 1.3–2.3 | 1.6(1.4–1.8) | 1.2–2.3 | < 0.001 | 1.7(1.6–1.8) | 1.5–1.9 | 1.7(1.6–1.8) | 1.4–1.9 | 0.288 |
Total protein | 7(6.8–7.2) | 5.9–7.9 | 7(6.9–7.1) | 6–7.7.7 | 0.752 | 7(6.9–7.3) | 6.2–8.2 | 7(7–7.2.2) | 6.4–8.4 | 0.74 |
Albumin | 4.1(3.9–4.3) | 3.5–4.9 | 4(4–4.2.2) | 3.4–4.9 | 0.934 | 4(3.8–4.1) | 3.3–4.7 | 4(3.9–4.1) | 3.3–4.8 | 0.099 |
ACR | 1188(800–1369) | 600–2735 | 819.5(512–987) | 237–1951 | < 0.001 | 1120(877–1333) | 600–3345 | 984(785–1211) | 314–3211 | < 0.001 |
FBS | 129(122–143) | 100–198 | 122.5(113–130) | 100–143 | < 0.001 | 140(125–166) | 120–199 | 133.5(125–154) | 113–177 | 0.006 |
2hpp Blood sugar | 165.5(145–189) | 56–276 | 145.5(130–160) | 34–201 | < 0.001 | 168.5(155–211) | 133–297 | 158.5(144–176) | 124–220 | < 0.001 |
HbA1c | 7.2(7.1–7.5) | 6.5–8.3 | 7.1(7–7.3.3) | 6.5–7.9 | < 0.001 | 7.1(7–7.5.5) | 6.5–8.3 | 7.1(7–7.3.3) | 6.4–8.4 | 0.032 |
GFR | 42.5(38–47) | 31–63 | 44.5(39–51) | 30–82 | < 0.001 | 43.5(35–50) | 30–62 | 43.5(37–50) | 31–66 | 0.482 |
Response to treatment: Stool H. pylori antigen after eradication therapy | ||||||||||
Negative N (%) | 36(72) | 28(56) | 0.096 | |||||||
Positive N (%) | 14(28) | 22(44) | ||||||||