Table 1 Clinical characteristics of AIS patients.

From: A bicentric study on the application of dual energy CT for predicting hemorrhagic transformation post endovascular thrombectomy

Characteristics

Total patients (n = 116)

HT patients (n = 36)

nHT patients(n = 80)

t/Z/χ2

P

Age (years), M(Q1, Q3)

58.00 (51.00, 70.00)

58.00 (51.00, 70.25)

57.50 (51.75, 69.25)

0.093

0.929

Gender

   

0.408

0.523

 Male (%)

79 (68.10)

26 (72.22)

53 (66.25)

  

 Female (%)

37 (31.90)

10 (27.78)

27 (33.75)

  

Weight (Kg), M(Q1, Q3)

70.00 (59.75, 75.00)

70.00 (62.00, 75.00)

69.50 (57.75, 75.22)

0.156

0.876

BMI, M(Q1, Q3)

24.95 (22.51, 26.95)

25.37 (23.23, 26.57)

24.86 (22.26, 27.25)

0.280

0.779

Hypertension (%)

91(79.45)

25 (69.44)

66 (82.50)

2.503

0.114

Diabetes (%)

82(70.69)

26 (72.22)

56 (70.00)

0.059

0.808

NIHSS on admission, M(Q1, Q3)

11.50 (6.00, 15.00)

14.50 (12.00, 17.00)

9.00 (4.00, 13.25)

4.775

< 0.001

ASPECTS on admission, M(Q1, Q3)

12.00 (9.00, 13.00)

9.00(7.00, 11.25)

13.00 (11.00, 13.00)

− 5.614

< 0.001

SBP (mmHg), M(Q1, Q3)

152.00 (137.75, 162.00)

147.50 (131.50, 157.00)

156.50 (141.00, 162.25)

− 2.254

0.024

DBP (mmHg), Mean ± SD

91.37 ± 14.64

88.22 ± 15.54

92.79 ± 14.09

− 1.563

0.121

GLU (mmol/L), M(Q1, Q3)

6.76 (5.77, 9.05)

8.26 (6.48, 11.05)

6.45 (5.63, 8.04)

3.023

0.003

RBC count (× 106/μL), Mean ± SD

4.46 ± 0.66

4.31 ± 0.61

4.53 ± 0.68

1.696

0.093

Hemoglobin (g/L), Mean ± SD

132.95 ± 19.65

130.11 ± 17.77

134.23 ± 20.42

1.043

0.299

PLT (× 109/L), M(Q1, Q3)

221.00 (189.75, 257.50)

216.50 (179.25, 234.50)

226.50 (193.50, 263.00)

− 1.155

0.248

LDL (mmol/L), M(Q1, Q3)

2.83 (2.24, 3.38)

2.78 (1.95, 3.41)

2.83 (2.40, 3.34)

− 1.277

0.202

TC (mmol/L), Mean ± SD

4.30 ± 1.02

4.20 ± 1.16

4.34 ± 0.95

− 0.683

0.496

TRIG (mmol/L), M(Q1, Q3)

1.19 (0.85, 1.64)

1.10 (0.81, 1.58)

1.21 (0.90, 1.66)

− 0.612

0.541

FIB (g/L), Mean ± SD

2.58 ± 0.96

2.63 ± 0.84

2.56 ± 1.00

0.345

0.731

INR, M(Q1, Q3)

1.02 (0.96, 1.08)

1.04 (0.98, 1.11)

1.00 (0.95, 1.06)

1.911

0.056

Ca2+(mmol/L), M(Q1, Q3)

2.11 (1.98, 2.19)

2.02 (1.97, 2.14)

2.13 (1.99, 2.20)

− 1.869

0.062

CRP (mg/L), M(Q1, Q3)

2.00 (0.50, 5.59)

2.14 (0.47, 6.69)

1.92 (0.500, 5.51)

0.155

0.877

Infarct location

   

NA

NA

 Right MCA territory (%)

37 (31.90)

18 (50.00)

19 (23.75)

  

 Left MCA territory (%)

48 (41.38)

14 (38.88)

34 (42.50)

  

 Right basal ganglia (%)

7 (6.03)

1 (2.78)

6 (7.50)

  

 Left basal ganglia (%)

10 (8.60)

1 (2.78)

9 (11.25)

  

 Brainstem (%)

2 (1.73)

1 (2.78)

1 (1.25)

  

 Right cerebellum (%)

2 (1.73)

0 (0.00)

2 (2.50)

  

 Left cerebellum (%)

2 (1.73)

0 (0.00)

2 (2.50)

  

 Other (%)

8 (6.90)

1 (2.78)

7 (8.75)

  

Hyperdense area on mixed energy CT

     

volume (mm3), M(Q1, Q3)

2342.00 (1632.00, 3267.00)

2366.50 (1801.00, 3244.00)

2143.00 (1546.50, 2938.50)

0.754

0.459

HT type

   

NA

NA

 HI- 1 (%)

11 (9.48)

11 (30.56)

0

  

 HI-2 (%)

4 (3.45)

4 (11.11)

0

  

 PH-1 (%)

10 (8.62)

10 (27.77)

0

  

 PH-2 (%)

6 (5.17)

6 (16.67)

0

  

 SAH (%)

1 (0.86)

1 (2.78)

0

  

 Remote PH (%)

4 (3.45)

4 (11.11)

0

  

 SICH (%)

11 (9.48)

11 (30.56)

0

  

mTICI

   

5.882

0.053

 2b (%)

17 (14.65)

9 (25.00)

8 (10.00)

  

 2c (%)

54 (46.56)

12 (33.33)

42 (52.50)

  

 3 (%)

45 (38.79)

15 (41.67)

30 (37.50)

  

Onset to thrombectomy (min), M(Q1, Q3)

322.50 (180.00, 431.50)

345.00 (240.00, 430.50)

316.50 (176.25, 431.50)

1.066

0.286

Onset to DECT (min), M(Q1, Q3)

1508.00 (1249.00,1813.00)

1447.00 (1176.75, 1825.75)

1526.00 (1311.00, 1804.00)

− 0.513

0.608

Thrombectomy to DECT (min), M(Q1, Q3)

1208 (838.75, 1417.5)

1000.00 (737.75, 1333.50)

1235.50 (1011.50, 1399.50)

− 1.805

0.071

  1. AIS, acute ischemic stroke; HT, hemorrhagic transformation; nHT, non-hemorrhagic transformation; M, median; Q1, 1st quartile; Q3, 3rd quartile; BMI, body mass index; NIHSS, National Institutes of Health Stroke scale; GLU, glucose; ASPECTS, Alberta stroke program early CT scores; SBP, systolic blood pressure; DBP, diastolic blood pressure; SD, standard deviation; GLU, glucose; RBC, red blood cell; PLT, platelet; LDL, low density lipoprotein; TC, total cholesterol; TRIG, triglycerides; FIB, fibrinogen; INR, international normalized ratio; Ca2+, serum calcium; CRP, C-reactive protein; MCA, middle cerebral artery; HI, hemorrhagic infarction; PH, parenchymal hematoma; SAH, subarachnoid hemorrhage; SICH, symptomatic intracranial hemorrhage; mTICI, modified thrombolysis in cerebral infarction; DECT, dual-energy computed tomography; t, t-test; Z, Mann–Whitney U test; χ2, chi-square test. Bold type indicates statistically significant differences.
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