Fig. 8
Analysis of therapeutic sensitivity. (A) Venn diagram depicts the overlap in sensitivity to the two most effective drugs. (B) Depictions of the molecular structures of the two candidate drugs. (C-H) Box plots depict the predicted IC50 values for two drugs, CCT007093 and A-443654, in high-risk and low-risk groups across four cohorts: TCGA-LUAD (C-D), GSE36741 (E–F), and GSE72094 (G-H). ROC analyses of risk scores were performed to evaluate their predictive accuracy for drug response. ****p < 0.0001.
