Fig. 4 | Scientific Reports

Fig. 4

From: METTL3 promotes vascular stability in intracranial aneurysm via m6A-AMPK axis

Fig. 4

METTL3 regulates IA progression in vivo via the AMPK signaling pathway. (A) Vessel thickness measurement of the arterial vessel in the IA rat model (scale bar = 100 μm). (B) Histological examination with HE staining and Masson’s trichrome staining of the arterial vessel in the IA rat model (scale bar = 50 μm). (C) Immunofluorescence double-staining to detect α-SMA and SM22α in the IA rat model (scale bar = 25 μm). These results reveal a downregulation of α-SMA and SM22α expression in the IA rat model compared to controls.

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