Table 29 Blinded expert diagnostic performance comparison.

From: Novel metaheuristic optimized latent diffusion framework for automated oral disease detection in public health screening

Pathology category

DentoSMART-LDM expert accuracy (95% CI)

Traditional method expert accuracy (95% CI)

Improvement (95% CI)

Expert confidence gain (95% CI)

Cohen’s d

t-statistic

p-value

Number needed to enhance

Early dental caries

91.7% (89.4–94.0)

73.4% (70.2–76.6)

+ 18.3% (14.8–21.8)

+ 24.7% (20.1–29.3)

1.34

12.67

< 0.001

5.5

Advanced dental caries

96.2% (94.7–97.7)

87.9% (85.8–90.0)

+ 8.3% (5.9–10.7)

+ 12.1% (8.7–15.5)

0.89

8.94

< 0.001

12.0

Periodontal disease

93.8% (91.9–95.7)

79.6% (76.8–82.4)

+ 14.2% (11.1–17.3)

+ 19.3% (15.2–23.4)

1.12

10.83

< 0.001

7.0

Apical periodontitis

89.4% (86.8–92.0)

71.2% (67.9–74.5)

+ 18.2% (14.3–22.1)

+ 22.8% (18.1–27.5)

1.28

11.94

< 0.001

5.5

Root resorption

84.6% (81.4–87.8)

62.8% (58.7–66.9)

+ 21.8% (17.1–26.5)

+ 28.4% (22.9–33.9)

1.52

14.23

< 0.001

4.6

Bone pathology

87.3% (84.5–90.1)

68.9% (65.2–72.6)

+ 18.4% (14.2–22.6)

+ 25.2% (20.1–30.3)

1.41

13.12

< 0.001

5.4

Cysts/tumors

82.1% (78.6–85.6)

59.7% (55.1–64.3)

+ 22.4% (17.3–27.5)

+ 31.6% (25.8–37.4)

1.67

15.84

< 0.001

4.5

Overall average

89.3% (88.2–90.4)

71.9% (70.5–73.3)

+ 17.4% (15.8–19.0)

+ 23.4% (21.2–25.6)

1.32

22.47

< 0.001

5.7