Table 4 Subgroup analyses of association between exposure to albumin and postoperative AKI using matched cohort.
Subgroup | Albumin non-exposure (N = 3697) | Albumin exposure (N = 1524) | Odds ratio (95% CI) | p-value | p for interaction |
|---|---|---|---|---|---|
Age | |||||
< 65 yr | 1868 (50.5) | 785 (51.5) | 2.00 (1.37–2.94) | < 0.001 | 0.33 |
≥ 65 yr | 1829 (49.5) | 739 (48.5) | 1.68 (1.20–2.35) | 0.003 | |
Sex | |||||
Female | 1159 (31.4) | 489 (32.1) | 2.10 (1.17–3.80) | 0.01 | 0.33 |
Male | 2536 (68.6) | 1035 (67.9) | 1.80 (1.35–2.39) | < 0.001 | |
ASA physical stats | |||||
1–2 | 3074 (83.1) | 1214 (79.7) | 1.99 (1.48–2.68) | < 0.001 | 0.43 |
3 | 623 (16.9) | 310 (20.3) | 1.34 (0.81–2.19) | 0.25 | |
Hypertension | |||||
No hypertension | 2269 (61.4) | 947 (62.1) | 2.38 (1.63–3.48) | < 0.001 | 0.008 |
Hypertension | 1428 (38.6) | 577 (37.9) | 1.49 (1.05–2.10) | 0.03 | |
Diabetes mellitus | |||||
No diabetes | 2934 (79.4) | 1199 (78.7) | 1.76 (1.31–2.36) | < 0.001 | 0.99 |
Diabetes | 763 (20.6) | 325 (21.3) | 2.12 (1.29–3.49) | 0.003 | |
Liver disease | |||||
No liver disease | 3442 (93.1) | 1422 (93.3) | 1.81 (1.39–2.35) | < 0.001 | 0.64 |
Liver disease | 255 (6.9) | 102 (6.7) | 2.04 (0.77–5.42) | 0.15 | |
