Table 5 Logistic regression analysis for the associations between uric acid (UA) and the risk of biological age acceleration, weighted.

From: Association of uric acid to high-density cholesterol ratio (UHR) with biological age acceleration: evidence from NHANES 2009–2018

 

Model 1

Model 2

Model 3

OR (95%CI)

p-value

OR (95%CI)

p-value

OR (95%CI)

p-value

Phenotypic age acceleration

Continuous†

1.68 (1.63,1.73)

< 0.001

1.45 (1.41,1.50)

< 0.001

1.40 (1.36,1.45)

< 0.001

Categories

      

Tertiles 1

Reference

Reference

Reference

Tertiles 2

1.72 (1.60,1.85)

< 0.001

1.33 (1.23,1.44)

< 0.001

1.30 (1.19,1.41)

< 0.001

Tertiles 3

3.11 (2.89,3.34)

< 0.001

2.05 (1.89,2.22)

< 0.001

1.91 (1.76,2.08)

< 0.001

p for trend

< 0.001

< 0.001

< 0.001

KDM age acceleration

Continuous†

1.44 (1.40,1.48)

< 0.001

1.53 (1.48,1.58)

< 0.001

1.49 (1.44,1.53)

< 0.001

Categories

      

Tertiles 1

Reference

Reference

Reference

Tertiles 2

1.33 (1.24,1.42)

< 0.001

1.41 (1.32,1.52)

< 0.001

1.37 (1.28,1.48)

< 0.001

Tertiles 3

2.10 (1.97,2.25)

< 0.001

2.35 (2.18,2.54)

< 0.001

2.20 (2.03,2.38)

< 0.001

p for trend

< 0.001

< 0.001

< 0.001

  1. Model 1 was crude model. Model 2 was adjusted for age, sex, and race. Model 3 was further adjusted for education level, alcohol consumption, smoking status, cardiovascular disease, hypertension, diabetes, cancer, and physical activity. Continuous†, standardized uric acid (UA). p for trend was tested by incorporating the variables of the median of each quartile into the regression model.
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